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C. On the next page is a figure of microtubule length over time during multiple cell cycles. Analyze the effect of paclitaxel as compared to control. Why does this data show paclitaxel can be an effective chemotherapeutic agent? Control 7.5 nM paclitaxel 20 15 m) Length ( 10 0 20 m) 15 Length ( 10 5 0 20 a 40 40 60 80 60 Time (seconds) 80 100 100 120 120 140 140 D. Microtubules require GTP (as an allosteric effector) to polymerize. How would you test this hypothesis? What would be your control(s)?

C. On the next page is a figure of microtubule length over time during multiple cell cycles. Analyze the effect of paclitaxel as compared to control. Why does this data show paclitaxel can be an effective chemotherapeutic agent? Control 7.5 nM paclitaxel 20 15 m) Length ( 10 0 20 m) 15 Length ( 10 5 0 20 a 40 40 60 80 60 Time (seconds) 80 100 100 120 120 140 140 D. Microtubules require GTP (as an allosteric effector) to polymerize. How would you test this hypothesis? What would be your control(s)?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Only need help with answers C and D please, thank you!

3. The chemotherapeutic agent, paclitaxel, stabilizes microtubules (proteins that are part of the cytoskeleton) which are shown in green below. Chemotherapeutic agents are meant to kill rapidly dividing cells. A. Why is confocal microscopy an appropriate tool to study the role of paclitaxel on the cytoskeleton and the cell cycle more generally? B. Why would paclitaxel be harmful to a cell? Draw a cell that has been treated with paclitaxel during cell division. C. On the next page is a figure of microtubule length over time during multiple cell cycles. Analyze the effect of paclitaxel as compared to control. Why does this data show paclitaxel can be an effective chemotherapeutic agent?
Transcribed Image Text:3. The chemotherapeutic agent, paclitaxel, stabilizes microtubules (proteins that are part of the cytoskeleton) which are shown in green below. Chemotherapeutic agents are meant to kill rapidly dividing cells. A. Why is confocal microscopy an appropriate tool to study the role of paclitaxel on the cytoskeleton and the cell cycle more generally? B. Why would paclitaxel be harmful to a cell? Draw a cell that has been treated with paclitaxel during cell division. C. On the next page is a figure of microtubule length over time during multiple cell cycles. Analyze the effect of paclitaxel as compared to control. Why does this data show paclitaxel can be an effective chemotherapeutic agent?
C. On the next page is a figure of microtubule length over time during multiple cell cycles. Analyze the effect of paclitaxel as compared to control. Why does this data show paclitaxel can be an effective chemotherapeutic agent? Control 7.5 nM paclitaxel 20 15 Length( 10 0 0 20 m) 15 Length ( 10 5 0 # 20 20 40 40 60 80 80 Time (seconds) 100 100 120 120 140 140 D. Microtubules require GTP (as an allosteric effector) to polymerize. How would you test this hypothesis? What would be your control(s)?
Transcribed Image Text:C. On the next page is a figure of microtubule length over time during multiple cell cycles. Analyze the effect of paclitaxel as compared to control. Why does this data show paclitaxel can be an effective chemotherapeutic agent? Control 7.5 nM paclitaxel 20 15 Length( 10 0 0 20 m) 15 Length ( 10 5 0 # 20 20 40 40 60 80 80 Time (seconds) 100 100 120 120 140 140 D. Microtubules require GTP (as an allosteric effector) to polymerize. How would you test this hypothesis? What would be your control(s)?
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