Question 22 2 pts You are a scientist studying the effects of arsenic on muscle cells. You read an article online claiming that arsenic is a competitive inhibitor of pyruvate dehydrogenase. You read another article claiming that arsenic is an allosteric inhibitor of pyruvate dehydrogenase. Match the following observations with the claim they would support if true. A. An effective treatment against arsenic poisoning is the addition of large amounts of pyruvate. Allosteric Inhibitor B. Arsenic binds to pyruvate dehydrogenase at a different site than where pyruvate binds. Competitive Inhibitor C. Arsenic reversibly binds to pyruvate dehydrogenase in the active site. Competitive Inhibitor D. Arsenic has a very different chemical structure than pyruvate. Allosteric Inhibitor

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
Question

You can choose either allosteric or competitive inhibitor for all questions.

Question 22
2 pts
You are a scientist studying the effects of arsenic on muscle cells. You read an article online
claiming that arsenic is a competitive inhibitor of pyruvate dehydrogenase. You read another article
claiming that arsenic is an allosteric inhibitor of pyruvate dehydrogenase. Match the following
observations with the claim they would support if true.
A. An effective treatment against arsenic poisoning is the addition of large amounts of pyruvate.
Allosteric Inhibitor
B. Arsenic binds to pyruvate dehydrogenase at a different site than where pyruvate binds.
Competitive Inhibitor
C. Arsenic reversibly binds to pyruvate dehydrogenase in the active site.
Competitive Inhibitor
D. Arsenic has a very different chemical structure than pyruvate. Allosteric Inhibitor
Transcribed Image Text:Question 22 2 pts You are a scientist studying the effects of arsenic on muscle cells. You read an article online claiming that arsenic is a competitive inhibitor of pyruvate dehydrogenase. You read another article claiming that arsenic is an allosteric inhibitor of pyruvate dehydrogenase. Match the following observations with the claim they would support if true. A. An effective treatment against arsenic poisoning is the addition of large amounts of pyruvate. Allosteric Inhibitor B. Arsenic binds to pyruvate dehydrogenase at a different site than where pyruvate binds. Competitive Inhibitor C. Arsenic reversibly binds to pyruvate dehydrogenase in the active site. Competitive Inhibitor D. Arsenic has a very different chemical structure than pyruvate. Allosteric Inhibitor
Expert Solution
Step 1

Pyruvate is acted upon by pyruvate dehydrogenase to convert pyruvate to acetyl-CoA. The acetyl-CoA enters The TCA cycle to generate ATP, NADH, and FADH2.

trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps

Blurred answer
Knowledge Booster
Biochemical activities
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON