(b) Describe or draw the response you would observed in cell C if an action potential occurred in cel B, closely followed by an action potential in cell A. = glutamate = AMPA receptor = GABA, receptor = GABA
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A:
Q: Describe two mechanisms by which ion channels are gated
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Q: Calculate: The equilibrium potential for potassium at room temp
A: Since you have asked multiple question, we will solve the first question for you. If you want any…
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- Describe how a very small quantity of receptor ligand is capable of eliciting a strong response in a target cell through amplification.Mr PL was administered Drug A that acts on a particular receptor. Unfortunately, it was given in overdose and produced an adverse effect. Drug B is then administered which blocks that receptor. The effect of drug B results in a reduction in the effect of drug A. Comment on if Drug B is acting competitively (reversibly) or non-competitively (irreversibly)? Provide one suitable clinically relevant example of such interaction.Both rhodopsin in vision and the muscarinic acetylcholine receptor in cardiac muscle are coupled to ion channels via G proteins. Describe the similarities and differences between these two systems.
- Write the summary of Mechanisms by Which Receptor Activation Influences Ion Channels?Match the receptor in column A with its ligand in column B.Which statement best describes the interaction that occurs as a result of the binding of a ligand to a ligand-gated ion channel receptor? A B с D ligand extracellular environment gate closed inactive ligand-gated ion channel receptor ions The process permanently opens or closes the ion channel. cytoplasm The process alters the membrane potential by changing the intracellular ionic concentration. The process causes G proteins to bind with GTP and become activated. The process removes three sodium ions from the cell and brings in two potassium ions.
- Describe the action of neurotransmitters at channellinked and G protein–linked receptors.Read the following statements (a) The resting nerve membrane is freely permeable to Na*, K* ions and negatively charged proteins. (b) The activity of Na* - K* pump is responsible for maintaining resting membrane potential. (c) The resting membrane is impermeable to negatively charged proteins present in the axoplasm. Choose the option representing correct statements. b only a and b b and c a, b and cThe drug Buckeyium binds to the NMDA receptor at the orthosteric binding site (were glutamate would normally bind). Assume that glycine is already bound, and that magnesium is not blocking the NMDAR ion channel. If the channel does not open as a result of Buckeyium binding than Buckeyium would be considered a
- Explain Receptor proteins.Outline the three general means by which binding of a water soluble extracellular chemical messenger to its matching surface membrane receptor brings about the desired intracellular response.Describe the contribution of each of the following to establishing and maintaining membrane potential: (a) the Na+K+ pump, (b) passive movement of K+ across the membrane, (c) passive movement of Na+ across the membrane, and (d) the large intracellular anions.