A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. Q. If trisomies and monosomies entailing chromosomes 13 and 22 are lethal, approximately what proportion of the surviving offspring are expected to be carriers of the translocation?

A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. Q. If trisomies and monosomies entailing chromosomes 13 and 22 are lethal, approximately what proportion of the surviving offspring are expected to be carriers of the translocation?

Name: A young couple is planning to have children. Knowing that there have b
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Description: A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that,

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter20: Chromosomes And Human Genetics

Section: Chapter Questions

Problem 3CT: People with Down syndrome have an extra copy of chromosome 21, for a total of 47 chromosomes....

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A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. Q. What types of zygotes will develop when each of gametes produced by the man fuses with a normal gamete produced by the woman?
A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. Q. List all the different types of gametes that might be produced by the man.
A young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. a. List all the different types of gametes that might be produced by the man. b. What types of zygotes will develop when each of gametes produced by the man fuses with a normal gamete produced by the woman? c. If trisomies and monosomies entailing chromosomes 13 and 22 are lethal, approximately what proportion of the surviving offspring are expected to be carriers of the translocation?
I. Give the chromosome number and chromosome configuration if the following mutations occurred in rice, a diploid organism wherein the number of chromosomes per set is 12. 1. Trisomy-11 2. Double Monosomy 3. Triploidy 4. Nullisomy-12 5. Tetraploid II. Give the chromosome number for the following: 6. 311+ 21 7. 4||+3||| 8. 2n=4 treated with colchicine to produce an autotetraploid 9. Monoploid maize (2n=20) 10, 51|^+ 51|B
B. A woman is a carrier of a Robertsonian translocation between chromosomes 18 and 21. (i) Her chromosome set with respect to chromosomes 18 and 21 would consist of which specific chromosomes. Please draw a DIAGRAM illustrating these chromosomes as they would appear in their unreplicated state, clearly labeling the chromosomes and the chromosome arms present. (ii) If this woman were to have a child with a man who possess a completely normal set of chromosomes, there are six different possible outcomes with respect to the combinations of chromosomes 18, 21, and Robertsonian translocation chromosome that could be present in their offspring. Please indicate the TYPES and NUMBERS of chromosomes of each type present in their potential offspring. You may label the chromosomes as follows: 18 (for chromosome 18), 21 (for chromosome 21) or 18/21 (for the Robertsonian translocation chromosome). Also, please indicate the specific genetic abnormality (if any) that would be present in…
A woman with no phenotype is known to have a 14:21 translocation. 1. With respect to only chromosomes 14 and 21, how many distinct chromosome combinations will happen in her eggs? What portion will be viable? 2. If she has children with a normal man (no translocations), what is the probability that they have a daughter with Down Syndrome or a son with no phenotype?
Diploid Number of chromosomes, Sex Chromosomes, (+/- whole) Chromosome (+/- partial) e.g. 47, XY, +14 = male with trisomy of chromosome 14 e.g. 46, XX, 1q+ = female with a partial increase to the length of the long arm of chromosome 1 (partial increases or decreases to a single chromosome still have the same diploid number) What is the notation for the following case? A man having Klinefelter syndrome and one Barr body.
In mice, 2n = 40. If a mouse cell divides by mitosis, it will produce two daughter cells that each have ________ chromosomes. If a mouse cell divides by meiosis, it will produce four daughter cells that each have ________ chromosomes. Type the appropriate number to fill in each blank (e.g., 40).
Diploid Number of chromosomes, Sex Chromosomes, (+/- whole) Chromosome (+/- partial) e.g. 47, XY, +14 = male with trisomy of chromosome 14 e.g. 46, XX, 1q+ = female with a partial increase to the length of the long arm of chromosome 1 (partial increases or decreases to a single chromosome still have the same diploid number) What is the notation for the following case A boy having Down syndrome
A man who is a carrier of a translocated 15/21 chromosome marries a genotypically normal woman. a. Show the possible gametes that will be formed by this man if the translocated 15/21 chromosome synapses with chromosome 21 at Prophase I.
Considering the following chromosome which is represented as a series of genes on each arm separated by the centromere. Describe the type of mutation required to produce each of the mutant chromosomes below. ABCDEFG*HIJKLMN
Diploid Number of chromosomes, Sex Chromosomes, (+/- whole) Chromosome (+/- partial) e.g. 47, XY, +14 = male with trisomy of chromosome 14 e.g. 46, XX, 1q+ = female with a partial increase to the length of the long arm of chromosome 1 (partial increases or decreases to a single chromosome still have the same diploid number) What is the notation for the following cases? ( A woman having Turner syndrome.