A mutant allele in persons with familial hypercholesterolemia (FH) causes death due to a lack of liver receptors for LDL. Susceptible persons have half the normal number of receptors, while other individuals have the normal number of receptors. In a phenotypically normal couple, the man had a female 1 cousin (on his father’s side) who died from FH; the woman had a maternal uncle with FH. Using standard symbols, draw a pedigree of these couple’s families. Write the genotypes of each family member.
A mutant allele in persons with familial hypercholesterolemia (FH) causes death due to a lack of liver receptors for LDL. Susceptible persons have half the normal number of receptors, while other individuals have the normal number of receptors. In a phenotypically normal couple, the man had a female 1 cousin (on his father’s side) who died from FH; the woman had a maternal uncle with FH. Using standard symbols, draw a pedigree of these couple’s families. Write the genotypes of each family member.
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter18: Genetics Of Behavior
Section: Chapter Questions
Problem 14QP: A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known...
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A mutant allele in persons with familial hypercholesterolemia (FH) causes death due to a lack of liver receptors for LDL. Susceptible persons have half the normal number of receptors, while other individuals have the normal number of receptors. In a
pedigree of these couple’s families. Write the genotypes of each family member.
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