A 52-year-old man has an episode of severe hematemesis. On physical examination there are no abnormal findings. An abdominal CT scan shows a small, nodular liver. Laboratory studies show Hgb 10.5 g/dL, Hct 31.1%, MCV 70 fL, platelet count 199,400/microliter, and WBC count 7370/microliter. His prothrombin time is 24 seconds (Normal: 11 to 15 seconds) and his partial thromboplastin time is 55 seconds (Normal 25 to 40 seconds). Which of the following is most likely to explain his findings? I. vonWillebrand disease ii.  Hemophilia Iii.Abnormal fibrinolysis iv.Myeloproliferative disorder V.Chronic viral hepatitis

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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A 52-year-old man has an episode of severe hematemesis. On physical examination there are no abnormal findings. An abdominal CT scan shows a small, nodular liver. Laboratory studies show Hgb 10.5 g/dL, Hct 31.1%, MCV 70 fL, platelet count 199,400/microliter, and WBC count 7370/microliter. His prothrombin time is 24 seconds (Normal: 11 to 15 seconds) and his partial thromboplastin time is 55 seconds (Normal 25 to 40 seconds). Which of the following is most likely to explain his findings?

I. vonWillebrand disease

ii.  Hemophilia

Iii.Abnormal fibrinolysis

iv.Myeloproliferative disorder

V.Chronic viral hepatitis

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