6. Label instructions for an ampicillin product call for the addition of 75 mL of water to make 100 mL of constituted suspension such that each 5 mL contains 150 mg of ampicillin. If a physician desires an ampicillin concentration of 100 mg/5 mL (rather than 150mg/5 mL), how many milliliters of water should be added to the dry powder?
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- 23. Vancomycin 2.5 g vial requires 50 mL of Sterile Water to produce a 50 mg/mL solution. What volume of Sterile Water for Injection is required to produce a 1 % (w/v) solution?1. Prepare 200 mL of an isotonic aqueous solution of thimerosal (MW 404.84; L iso 3.4). The concentration of this antiinfective drug is 1:5000. a. Calculate the E value. b. Adjust the Isotonicity of the solution using NaCl.1. The prescription for an oral solution reads “1 tbsp ac & hs x 10d.” What is the minimum (in mL) of solution should you dispense? 2. A nursing floor requires half liter of 50% isopropyl alcohol. How many mL of 70% isopropyl alcohol will be needed for compounding this order? 3. How may grams of pure dextrose is needed to prepare 100cc of D50W?
- 6. A solution made up of 500 mL of 50% dextrose, 500 mL of 8.5% Aminosyn, and 300mL of sterile water for injection is ordered. a) What is the total weight (in grams) of the dextrose? b) What is the total weight (in grams) of Aminosyn? c) 20 mEq of KCI are needed in the infusion above. How many mL of KCI should be added? Stock strength available: KCl 2 mEq/mL d) 22 mEq of NaCl are also needed in the infusion. What volume of NaCl should be added? Stock strength available: NaCl 4.4 mEq/mL e) What is the total volume of solution with the original fluids and the addition of KCI and NaCl?1. Study the given drug label and answer the question that follows. Show your solution How many total milliliters of diluent are used? What is the final concentration for each drug? a. b. C. How many milliliters are administered to give amoxicillin 500 mg/clavulanate 125 mg? J 343598 00451 AUGMENTIN 250 mg/5 mL 250 mg/5 mL NDC 43598-004-51 Directions for mixing: Tap bottle until all powder flows freely. Add approximately 2/3 of total water for reconstitution (total=65) shake vigorously to wet powder. Add remaining water, again shake vigorously. Dosage: See accompanying prescribing information. Keep tightly closed. Shake well before using. Must be refrigerated. Diecard after 10 days. Your answer AUGMENTIN® AMOXICILLIN/CLAVULANATE POTASSIUM FOR ORAL SUSPENSION When reconstituted, each 5 mL contains: AMOXICILLIN, 250 MG, as the trihydrate CLAVULANIC ACID, 62.5 MG, as clavulanate potassium 75 mL (when reconstituted) DR.REDDY'S Rx only Use only if inner seal is intact. Not contents:…1. What is the concentration of the solution prepared by diluting 50 µl of ampicillin (1.0mg/ml) to a final volume of 1ml? 2. Determine the volumes of phenol, chloroform, and isoamyl alcohol required to prepare250 ml of a 25:24:1 (v/v) solution.
- 7. If a pharmacist dissolved the contents of eight capsules, each containing 300 mg of clindamycin phosphate, into a sufficient amount of an astringent liquid base to prepare 60 mL of topical solution, what would be the percentage strength (w/v) of clindamycin phosphate in the pre- scription? 7. 4% w/v clindamycin phosphateConsider the following from the Ampicillin for Injection, USP package insert: For Intramuscular Use: Label Claim 250mg 500mg 1g 2g Amount of Diluent (mL) Approx. Volume (ml) 0.9 1.7 3.4 6.8 1 2 4 8 a) What is the amount of diluent needed to reconstitute a 1 g vial? b) What is the powder volume for a 1 g vial of ampicillin? Approx. Concentration (mg/mL) 250 250 250 250 Later in the package insert you see: For Direct Intravenous Use: Add 5 mL Sterile Water for Injection or Bacteriostatic Water for Injection to the 250 and 500 mg vials and administer slowly over a 3 to 5-minute period. Ampicillin for Injection, 1 g or 2 g, may also be given by direct intravenous administration. Dissolve in 7.4 or 14.8 mL Sterile Water for Injection or Bacteriostatic Water for Injection, respectively, and administer slowly over at least 10 to 15 minutes. c) What is the amount of diluent needed to reconstitute a 1 g vial of ampicillin for direct IV injection d) What is the total amount of volume that will…5) "The doctor orders Pfizerpen 300,000 units q6h. How much will the patient receive if the medication is reconstituted with 8.2 mL diluent? (Concentration on label says 500,000 units/mL which is associated with 8.2 mL diluent). Answer:
- 2. Provide a one-sentence broad generalization regarding the % acrylamide one should use in SDS PAGE gels and the MW range targeted. 3. Name and give the purpose of each component in the electrophoresis buffer (specify type and pH) used for SDS PAGE.1. Prepare 30 mL of a 5 mg/mL oral phenobarbital solution using phenobarbital available from the manufacturer in a 65 mg/mL solution that comes in 1-mL vials. How much stock solution will be required? 2. What mass in milligrams of potassium nitrate is present in 0.25 kg of a 500 ppm aqueous solution of KNO,?17. If an intravenous injection contains 20% (w/v) of mannitol, how many milliliters of the injection should be administered to provide a patient with 100 g of mannitol? 17. 500 mL