3-Which of the following is TRUE about sickle cell disease (SCD)? Select allthat apply.A. Sickle cell anemia (SCD) is an inherited disorder of the hemoglobin inblood.B. Sickle cell anemia requires the inheritance of two sickle cell genes.C. Sickle cell trait, which is the inheritance of one sickle gene, almost nevercauses problems.D. Virtually all of the major symptoms of sickle cell anemia are the direct resultof the abnormally shaped sickled red blood cells obstructing the flow of blood.E. all that apply4-In children diagnosed with sickle cell disease (SCD), tissue damage resultsfrom which of the following?A. Air hunger and respiratory alkalosis due to deoxygenated red blood cells.B. Hypersensitivity of the central nervous system (CNS) due to elevatedserum bilirubin levelsC. A general inflammatory response due to an autoimmune reaction fromhypoxiaD. Local tissue damage with ischemia and necrosis due to obstructedcirculation

Sickle cell anemia is a disease characterized by the change of red blood cells from round to sickle…

Answered: 3-Which of the following is TRUE about…

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter16: Human Genetics And The Human Genome

Section: Chapter Questions

Problem 6TYU

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1. Which of the following WBC originate from common myeloid procursor (CMP) lineage? A. T lymphocyte B. Neutrophil C. B lymphocyte D. all of the above 2. Which of the following WBC originate from common lymphoid precursor (CLP) lineage? A. Neutrophil B. Basophil C. Platelet D. T lymphocyte 3. Which of the foolwing cells releases heparin and histamin during inflammation? A. basophil B. mast cell C. eosinophil D. neutrophil 4. Which of the following cytokines is/are responsible for the pain of inflammation? A. histamine B. bradykinin C. prostaglandin D. A & B are true E. B & C are true
1. Differentiate leukemia from lymphoma and myeloma as to: a. hallmark cells / blood features b. organ in the body affected 2. In the 6 factors related to the occurrence of leukemia, rank them in order in which you think is the most related (1 for most related, 6 for least related). Give the reason for your ranking. 3. Rationalize why most leukemic patient die of infection. 4. In patients with leukemia, there is fatigue, weight loss, easy bruisability. Why do you think this is so?
8. Compare the job of the abnormal hemoglobin protein that causes sickle cell disease to the normal hemoglobin protein. Explain how this causes sickle cell disease.
1 Which of the following is/are true for sickle-cell anemia? I. It results from a point mutation on the beta sub-unit which results to the amino acid substitution of V with E. II. The sickle-shaped RBC's are vaso-occluded in the capillaries resulting to damage in various internal organs. III. Hemoglobin precipitates when deoxygenated, resulting to the distortion in the shape of the thrombocytes. Select the correct response: l and Ill I, II, and Ill I only Ill only ll and Ill Il only I and Il
1.These permit easier movement of cells between tissues and blood.A. sinusoid capillariesB. continuous capillariesC. fenestrated capillariesD. metarterioles2. The white pulp of spleen _____.A. produce blood cellsB. store plateletsC. destroy blood borne pathogensD. remove defective blood cells 3. Which of the following is TRUE?A. Tonsillitis of viral origin usually resolves on its own.B. Pharyngeal tonsillitis are pairedC. Tonsillitis are caused by viruses onlyD. Lingual tonsils are commonly removed in tonsillectomy 4. What will take over the functions of spleen if spleen is removed?A. thymus and liverB. red bone marrow and thymusC. lymph nodes and thymusD. red bone marrow and liver 5. Tissues that lack lymphatic capillaries include ______.A. Red bone marrow B. thymus C. lymph gland D. all of the above 6. Which of the following describes an artery?A. round and larger lumenB. without valveC. lumen is large when blood is flowingD. with valve
1. The number of white blood cells in the circulating blood is 4,300 to 10,800 per milliliter and their main function is in: a. Participation in the immune response of the body b. Carrying oxygen to the cells of the body c.Blood dlotting d. Liver function 2. The cytoplasm of these cells have large dark granules that contain heparin nd histamine: 2. Neutrophils b, Eosinophils c. Basophils d. Monocytes
3. A woman who is a carrier for hemophilia marries a normal man. a. What is the probability that their first child will be a hemophiliac girl? b. What is the probability that the child will be a girl who is a carrier for the disease? c. What is the probability that, if they have a son, he will be normal? d. What is the probability that they will have a son who is a carrier for the disease?
1. Regarding Sickle Cell Disease all are correct except one ○ a. Occur in alpha haemoglobin ○ b. Results from a single amino acid substitution ○ c. An inherited blood disorder ○ d. Red blood cell can not carrying oxygen
7. Hematopoiesis refers to I Multipotent haematopoietic stem cells are involved in this process II. the production of RBCS within the red marrow cavities of the spongy bones III the formation of blood cells within the yellow marrow in the međullary cavities of bones IV. the formation of all of the cellular components of blood within the red marrow cavities of the spongy bones А. I В. IV C. both I and II D. both I and III E. both I and IV F. All choices are correct
10. What is an anemia? 11. What is the genetic mutation associated with sickle cell? 12. Compare and contrast sickle cell disease versus sickle cell trait? Think about causes, age of diagnosis, signs and symptoms, when do these conditions become problematic to health? how might they differ on lab tests 13. In which populations and/or regions of the world does sickle cell disease and sickle trait most commonly appear? Speculate why this might be? 14. Define exertional sickling? Why is this relevant to the case study presented in class?
5. This may elevate the risk for cerebral microbleeds in patients with hemophilia a.All of the above b.Hepatitis C infection c.Increased age d.Cardiovascular risk factors 6. The prenatal counselling and delivery planning is discussed for a pregnant with hemophilia. Which of the following statements is true: a.Vaginal delivery is recommended based on the low overall risk of bleeding with vaginal delivery in a neonate with severe hemophilia b. The patients should have maternal factor levels drawn regardless of planned delivery route c. Cesarean delivery is recommended based on the increased risk of intracerebral hemorrhage associated with a trial of labor d. None of the choices
1 Mark the following statements as true (T) or false (F). If the statement is false, correct it to make it a true statement. Red blood cells are also known as leukocytes. a. b. White blood cells with granules in their cytoplasm are known as agranulocytes. The granulocytes include the neutrophils, eosinophils, and basophils. с. d. Erythrocytes carry oxygen through the body on the protein hemoglobin. е. Both lymphocytes and monocytes are granulocytes. f. Platelets are fully formed cells involved in blood clotting. 2 Label the formed elements on the peripheral blood smear in Figure 11.11. FIGURE 11.11 Peripheral blood smear 3 Which of the following is not an antigen that may be found on the surface of an erythrocyte? a. A antigen b. B antigen c. O antigen d. Rh antigen

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