13. Cystic fibrosis is caused by a recessive lethal gene and can be detected by an excess concentration of chloride in sweat. If a sweat test reveals a man to be heterozygous and his wife to be homozygous normal, what are the chances that their children will have the disease? Could any of their grandchildren have the disease?

13. Cystic fibrosis is caused by a recessive lethal gene and can be detected by an excess concentration of chloride in sweat. If a sweat test reveals a man to be heterozygous and his wife to be homozygous normal, what are the chances that their children will have the disease? Could any of their grandchildren have the disease?

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter13: Modern Understandings Of Inheritance

Section: Chapter Questions

Problem 11RQ: The genotype XXY corresponds to Klinefelter syndrome Turner syndrome Triplo-X Jacob syndrome

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6. Hemophilia causes severe bleeding from minor wounds. The blood is unable to clot properly because one of the factors necessary for clotting is missing. Hemophilia is an inherited sex-linked recessive disorder transmitted on the X chromosome by mothers to their sons. i) A woman inherited the gene for hemophilia from her mother and marries a man who iş normal and has no hemophilia. What is the possibility that her children can have hemophilia?
1. Given the karyotype shown here, is this a male or a female? What would the genotype/phenotype of this individual be?
6. A man with X-linked colorblindness marries a woman with no history of ibba colorblindness in her family. The daughter of this couple marries a normal man noitenmot and ended up hone daughter, and their daughter also marries a normal man. This mont blast couple has already had a child with color blindness. do sri ni novig A) What is the chance that next child will be color blind? B) What is the chance that this last couple will have an affected daughter? (d #50x²50 (
2. The common grandfather of two first cousins has hereditary hemochromatosis, a recessive condition causing an abnormal buildup of iron in the body. Neither ofthe cousins has the disease nor do any of their relatives.a. If the first cousins had a child, what is the chancethat the child would have hemochromatosis?Assume that the unrelated, unaffected parents ofthe cousins are not carriers.b. How would your calculation change if you knewthat 1 out of every 10 unaffected people in the population (including the unrelated parents of thesecousins) was a carrier for hemochromatosis?
5. A man who is not bald married a non bald female whose mother is bald. A. What is the chance that the couple will have a bald son? B. What is the probability that the couple will have a bald daughter? What is the chance that the couple will have a nonbald daughter? C.
1. In humans, the allele for normal blood clotting, H, is dominant to the allele for hemophilia, h. This is a sex-linked trait found on the X chromosome. A woman with normal blood clotting has four children: a normal son, a hemophiliac son, and two normal daughters. The father has normal blood clotting. What is the genotype for each member of the family?
3. STATEMENT: Color-blindness is due to a sex-linked recessive gene. A colorblind man marries a normal-visioned woman and they have a colorblind daughter. a) What is the genotype for the man, woman and the daughter? b) The couple decides to have another child, what is the probability their child will be: i. Colorblind? ii. Have a daughter that has normal vision, no colorblindness? They know that they're having a son because they saw the sonogram with a little noticeable Schmeckle (Oscar Meyer weiner). iii.
3a. A father that is A+ has a child with a mother that is B+. If each parent carries the recessive i allele (aka the o allele) and each parent is heterozyogous for the Rh allele, what is the chance that they have a child that is O+?
21. Assuming sexual reproduction and that no mutations have occurred, which of the following offspring genotypes is NOT possible for the given parent genotypes? (LS3-1) * Genotype Genotype Genotype B Genotype Genotype Genotype K K G G B B W Genotype A Genotype B Genotype C O Genotype D
3. The father shown beiow has Hemophilia, an X-linked recessive disorder. If this couple had a son, could the son have the disease? What genotype(s) would be possible for that son?
2. STATEMENT: A woman and man both do not have sickle-cell anemia, but both had one parent who had sickle cell. Sickle-cell is an autosomal (somatic) recessive trait. a) What is the genotype for the woman, man and each of their parents? b) This couple unexpectedly is going to have their first child. i. What's the probability that their child will have not have sickle cell like the couple? ii. What's the probability that the child will have sickle cell like one the grandparents?
7. In a disputed parentage case, the child is blood type O, while the mother is blood type A. What blood type would exclude a male from being the father? Would the other blood types prove that a particular male was the father?