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1. What volume of sterile water for injection (diluent) must be added to reconstitue the powder? 2. How many mL of the reconstituted cefazolin is needed to prepare the final product?

1. What volume of sterile water for injection (diluent) must be added to reconstitue the powder? 2. How many mL of the reconstituted cefazolin is needed to prepare the final product?

Curren'S Math For Meds: Dosages & Sol
Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 7.10P
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1. What volume of sterile water for injection (diluent) must be added to reconstitue the powder?

2. How many mL of the reconstituted cefazolin is needed to prepare the final product?

Preparation of Parenteral Solution Parenteral drug products should be SHAKEN WELL when reconstituted, and inspected visually for particulate matter prior to administration. If particulate matter is evident in reconstituted fluids, the drug solutions should be discarded. When reconstituted or diluted according to the instructions below, Cefazolin for Injection is stable for 24 hours at room temperature or for 10 days if stored under refrigeration (5°C or 41°F). Reconstituted solutions may range in color from pale yellow to yellow without a change in potency. Single-Dose Vials For IM injection, IV direct (bolus) injection or IV infusion, reconstitute with Sterile Water for Injection according to the following table. SHAKE WELL. Vial Size Amount of Diluent Approximate Concentration Approximate Available Volume 500 mg 1 gram 2 mL 2.5 mL 225 mg/mL 330 mg/mL 2.2 mL 3 mL
Transcribed Image Text:Preparation of Parenteral Solution Parenteral drug products should be SHAKEN WELL when reconstituted, and inspected visually for particulate matter prior to administration. If particulate matter is evident in reconstituted fluids, the drug solutions should be discarded. When reconstituted or diluted according to the instructions below, Cefazolin for Injection is stable for 24 hours at room temperature or for 10 days if stored under refrigeration (5°C or 41°F). Reconstituted solutions may range in color from pale yellow to yellow without a change in potency. Single-Dose Vials For IM injection, IV direct (bolus) injection or IV infusion, reconstitute with Sterile Water for Injection according to the following table. SHAKE WELL. Vial Size Amount of Diluent Approximate Concentration Approximate Available Volume 500 mg 1 gram 2 mL 2.5 mL 225 mg/mL 330 mg/mL 2.2 mL 3 mL
Cefazolin 15 mg/mL 50 mL Cefazolin (1 gm powder for injection)_750 mg Sodium Chloride 0.9% 50 mL Tech: Made: B CEFAZOLIN for Injection, USP 1 gram 19 For IM or IV Use RPh: Expires: [Cefazolin 1gm powder for injection package insert]
Transcribed Image Text:Cefazolin 15 mg/mL 50 mL Cefazolin (1 gm powder for injection)_750 mg Sodium Chloride 0.9% 50 mL Tech: Made: B CEFAZOLIN for Injection, USP 1 gram 19 For IM or IV Use RPh: Expires: [Cefazolin 1gm powder for injection package insert]
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