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Metabolic Syndrome Analysis

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Metabolic syndrome is a group of disorders that predisposes to the cardiovascular disorders and constituted a significant risk for coronary heart disease, however, its effect on gene expression pattern is unclear. The considerable evidence demonstrated that genetic factors predispose to the cardiovascular complications. Metabolic syndrome significantly alters cardiac gene expression profile which may be involved in the development of cardiovascular disease. In this study we have measured MMP9 and COX-2 genes expression in cardiovascular patients with metabolic syndrome and those without metabolic syndrome. COX-2 is associated with increased prostaglandin I2 (PGI2 or prostacyclin) production by vascular endothelium. Prostacyclin (PGI2) is

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