Lab Instructions_ Cell Biology Act I Mission Memo (Spring A 2024 Onward)

Question: 1. Cytotoxic drugs that are commonly used in chemotherapy damage the genome of tumor cells, thereby provoking death of cancer cells. Relative to cancer cells, would you expect normal cells to be more sensitive or less sensitive to chemotherapy? Explain your reasoning. (answer in five sentences or less).

question: Can you summarize and explain for me what you want to tell in the article below? Can you explain the figure?  When I read it myself, I do not understand exactly what is meant by the article. It would be nice if you could highlight the important points. You can use them in a figure or diagram to explain. thank you and hava a nice day :) Article:  Nanotechnology Tools to Detect SARS-CoV-2 Standard procedures for detecting the virus from nasopharyngeal and/or oropharyngeal swabs have been reviewed recently and are primarily based on reverse transcription polymerase chain reaction (RT-PCR). Here, we would like to mention some preliminary ideas on nanotechnology-based assays to monitor the presence of SARS-CoV-2. A simplified test and variants thereof to detect viral proteins (e.g., HIV or influenza virus) without the need for expensive equipment is based on the color change of Au NPs bound to antibodies. Similar to the enzyme-linked immunosorbent assay (ELISA) antibodies coupled…

QUESTION: A 35-year-old man is known to have been HIV-positive for the past 10 years. Physical examination now shows multiple reddish purple, nodular skin lesions with the microscopic appearance shown in the figure. These lesions have been slowly increasing for the past year. Which of the following risk factors is most likely to play a role in the development of these skin lesions? A Antiretroviral therapy B Epstein-Barr virus infection C Hyperlipidemia D Mycobacterium avium complex infection E Sexual intercourse do fast please

Need detail explanation Scenario: A 56-year-old client was diagnosed with aggressive bone cancer that required a below the knee amputation of the left leg 14 months ago. The client received recommended chemotherapy and radiation, but it was found recently that the cancer has metastasized to the chest and skull. There is lymph node involvement with a primary tumor partially obstructing the right kidney. The client was readmitted 4 days ago for removal of the remaining portion of the left leg and was told that there is no appropriate surgical or medical intervention that would be beneficial at this point in the disease process. The interdisciplinary health care team has recommended palliative care upon discharge since the client’s life expectancy is between 3 and 5 months. The client has developed a mutually respectful relationship with a nurse on the unit who has provided care throughout all previous hospitalizations. The client shares with the licensed practical nurse (LPN) that, “I…

Question:- Why is it important for a cancer cell to undergo phenotypic changes to be able to metastasize to distant organs? Describe briefly the two transitions that cells undergo during this process. How can you identify metastasis from a solid tumor in a lymph node?

question: Can you summarize and explain for me what you want to tell in the article below? When I read it myself, I do not understand exactly what is meant by the article. It would be nice if you could highlight the important points. You can use them in a figure or diagram to explain. thank you and hava a nice day :) Article: Nanomaterial-Based Vaccine Development and Immunomodulation Following the publication of the genetic sequence of SARS-CoV-2 on January 11, 2020, intense research efforts have been devoted to developing a vaccine against COVID-19. With unprecedented speed, this extraordinary scientific mobilization led the first vaccine candidate to enter the Phase I human clinical trial on March 16, 2020, and other novel candidates are rapidly following. Up to May 22, 2020, there are 10 COVID-19 candidate vaccines in clinical evaluations and 114 in preclinical development.  Concerning vaccine and immunization research, nanomaterials can assist in multiple ways to boost the…

how do i expand this into 1000 words for a result section of a report   The objective is to interpret the results of an RNA-Seq analysis to identify differentially expressed genes in breast cancer using figure 1. The data provided includes gene symbols, chromosome location, start and end points, strand, fold change, log2 fold change, p-value, and false discovery rate (FDR). The RNA-Seq analysis has identified several genes that are differentially expressed in breast cancer. These genes are located on various chromosomes and have varying levels of fold change, indicating the degree to which their expression levels differ between normal and cancerous cells. The gene with the highest fold change is EYA4, located on chromosome 6, with a fold change of 3604.4176. This indicates that the expression of this gene is over 3600 times higher in cancer cells compared to normal cells. The log2 fold change is 11.81555, which is a measure of the magnitude of the difference in gene expression. The…

Answer and explain your choice to the following multiple-choice questions about cancer-promoting mutations. The ABC gene undergoes multiple gene duplication events, producing multiple copies of this gene in the genome. This gene duplication event is associated with cancer. What would best describe the normal function of ABC gene? Inhibit cell growth and division Oncogene Inhibit apoptosis Metabolic enzyme EXPLAIN in 1-2 sentences: A mutation in the epidermal growth factor receptor (EGFR) causes it to send a positive signal along its intracellular signaling pathway, even without the EGF ligand bound to it. Knowing the function of a growth factor, how would you classify this mutation? an activating mutation in a tumor suppressor gene an activating mutation in a proto-oncogene a loss of function mutation in a tumor suppressor gene a loss of function mutation in a proto-oncogene EXPLAIN in 1-2 sentences: In an otherwise normal cell, what would be the immediate result of a…

Question :- If the total cancer risk is 100 cancers/104 people/Sv, what is the cancer risk incurred by an occupationally exposed worker who received 1 cGy/year, each year, for 20 years? How does this compare with the national cancer risk?

shift T ctrl caps lock tab VILION fn Quiz Submissions - Take: Unit D Practice Quiz JUDITH BIRECH (username: nj2191ne) Attempt 1 Written: Feb 9, 2023 2:20 PM - Feb 9, 2023 3:06 PM Submission View Released: Feb 13, 2023 12:01 AM Question 2 A patient had decreased mast cells. Which do you predict? K a) decreased histamine & increased inflammation Ob) increased histamine & increased inflammation 34°F Sunny /" @ Q ion x360 Laptop ment anywhere A Z W ■ 3 S E 4 alt % الالالال التاكاك R O Search 5 F T 6 8 9 ||G|H|J|K M

courses/49703/quizzes/244266/take/questions/4605424 at is cieariy outside tne scope or our iecture fiotes anid labs Tor any reason, your score W ro. ote***You are allowed to use blank scratch paper to help you on the exam. nank you for your cooperation everyone, and good luck! Question 4 What term is most closely associated with the term "differentiation"? new growth O taking on a cellular fate O mitosis O genetic mutation O translation « Previous No new data to save. Last checked at 9:42. FEB 23

Question: Why does the term expired mean that a patient has died?

3:53 1 + t A 42.0 KB/S 7i ul l 62 chegg.com/homework-h 1 home / study / science / anatomy and physiology / anatomy and physiology questions and answers / asked with an image Your question has been posted. We'll notify you when a Chegg Expert has answered. Post another question. O Next time just snap a photo of your problem. No typing, no scanning, no explanation required. Get Chegg Study App Question: O Edit question Nerve Origin Movements muscles innervated Cutaneous or sensory innervation allary radial Muscilo-cutaneous ulnar median obturator Femoral nerve tibial Common fibular nerves Deep fibular nerve Superficial fibular nerve Sciatic nerve Gluteal nerves Pudendal nerves Mioinguinal nerve Lumbosacral nerves Expert Answero This question hasn't been answered COMPANY LEGAL & POLICIES CHEGO PRODUCTS AND SERVICES CHEGO NETWORK About Chegg Chegg For Good College Marketing Mobile Apps EasyBib Internships.com Advertising Choices Cheap Textbooks Cookie Notice Chegg Coupon Sell Textbooks…

Question:- The success of renal transplantation depends on three human histocompatibility genes, HLA-A, HLA-B and HLA-C, which must match between the donor and the receiver. A single mismatch may cause the kidney rejection. Each gene has multiple co-dominant alleles. These three genes are located very close to each other on chromosome 6, so that the recombination rate is very low (below 1%). The father has the following genotype: A1, A2, B24, B10, Cw4 and Cw7 and the mother is A1, A1, B11, B7, Cw5 and Cw8. Their first boy is A1, A1, B24, B11, Cw7 and Cw8. What is the probability that the second child is compatible with his/her brother?

Question:- 1. Describe an assay that could measure the activity of adenylyl cyclase (AC).

Question: Some scientists have concluded that this method of gene therapy will be a more effective long-term treatment for SCD than HSCT. Use all the information provided to evaluate this conclusion. I dont know how to answer this question pls help:(

The question that I need help with is : Explain why cells in the human body have the same DNA but different structures and functions?

Looking at Figure 1, what did Romansik et al. (2007) find regarding the relationship between the mitotic index and tumor grades. Explain their findings in your own words. Use specific details from Figure 1.    The research paper is here: https://journals.sagepub.com/doi/10.1354/vp.44-3-335

Discussion: (1 or 2 paragraphs with your own opinion like how Circulating Tumor DNA as Biomarkers for Cancer Detection technology can be early detector of cancer)

how do i expand this into 1000 words The methodology employed to identify differentially expressed genes (DEGs) in breast cancer using RNA-Seq data involves several systematic steps integrating data retrieval, analysis, normalization, DEG identification, and functional annotation. Initially, raw RNA-Seq data is retrieved from the NCBI GEO database, specifically from dataset GSE216238 (Nakshatri, 2023), which encompasses samples from both breast cancer and normal tissue. Subsequently, the raw data was imported into Excel for initial analysis, leveraging its widespread availability and user-friendly interface. Gene expression data for breast cancer analysis was obtained from the Gene Expression Omnibus (GEO) database. The GEO homepage (https://www.ncbi.nlm.nih.gov/geo/) was accessed, and the "Query & Browse" tab was selected. Advanced Search: Under "Search GEO DataSets," an advanced search was conducted (https://www.ncbi.nlm.nih.gov/gds/advanced). Keywords "breast" and "cancer" were…

List several reasons why angiogenesis is a very active area for cancer therapy research.

Which type of stem cell therapy may cause some ethical issues and may results in benign tumor? (Name only, no description required)

question: Can you summarize and explain for me what you want to tell in the article below? When I read it myself, I do not understand exactly what is meant by the article. It would be nice if you could highlight the important points. You can use them in a figure or diagram to explain. thank you and hava a nice day :) Article: Interference with Cellular Uptake, Immobilization, and Inactivation of the Virus Outside of the Host Cell Nanomaterials can be synthesized with a high specific surface area of a few hundred square meters per gram. Therefore, dependent on the surface properties, nanomaterials efficiently adsorb biomolecules and form a so-called biomolecular corona. This passive, nontargeted adsorption might be utilized to bind viruses, provided that the selected nanomaterial is relatively biocompatible. Viral surface proteins are often modified by sugar moieties or encompass positively charged amino acid patches that bind to lectins or glycosaminoglycans (GAGs) of heparan sulfate…

how do i expand this into 1000 words The objective is to interpret the results of an RNA-Seq analysis to identify differentially expressed genes in breast cancer using figure 1. The data provided includes gene symbols, chromosome location, start and end points, strand, fold change, log2 fold change, p-value, and false discovery rate (FDR). The RNA-Seq analysis has identified several genes that are differentially expressed in breast cancer. These genes are located on various chromosomes and have varying levels of fold change, indicating the degree to which their expression levels differ between normal and cancerous cells. The gene with the highest fold change is EYA4, located on chromosome 6, with a fold change of 3604.4176. This indicates that the expression of this gene is over 3600 times higher in cancer cells compared to normal cells. The log2 fold change is 11.81555, which is a measure of the magnitude of the difference in gene expression. The p-value for this gene is extremely low…

Question:- Your patient has a three month history of weight loss, night sweats, and swollen lymph nodes. He has been seen for numerous opportunistic infections. These are infections by pathogens that usually do not cause significant disease in humans. He has a history of IV drug abuse and admits to having shared used needles with other drug abusers. You suspect he has Acquired Immune Deficiency Syndrome (AIDS). The virology lab is having technical difficulties right now and is unable to test for the presence of Human Immunodeficiency virus. However, the hematology lab is able to test for the presence of different types of lymphocytes. If patient does have AIDS, which type of lymphocyte would be most affected and would the numbers of this lymphocyte be increased or decreased?

Question:- When researchers test a new drug using two similar groups of mice, the group of mice that receive the placebo constitute the ______

For many years, targeted therapies for cancer treatment continue to be developed, however more and more patients are developing resistance to targeted therapies. Discuss one mechanism of resistance to targeted therapies for cancer and provide an example of how might creatively combat it using clinical concepts.

Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs.  Question: What kind of systems have been developed to detect CSCs? Describe by giving examples.  Please explain in detail the main findings with your own words.

Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs.  Question: What is the importance and advanatge of detecting CSCs?

Question 1. Describe and explain the epidemiological evidence supporting the view that cancer develops through a multi-step process involving increasingly severe stages.. Question 2. Describe and explain the genetic evidence supporting the view that cancer develops through a multi-step process involving increasingly severe stages.

Discuss why cancer treatment may involve a combinationof chemotherapy, radiation therapy, and surgery.